Hyperplastic Discs Differentially Regulates the Transcriptional Outputs of Hedgehog Signaling

Hedgehog (Hh) acts as a morphogen to activate the transcription of diverse target genes via its downstream effector Cubitus interruptus (Ci). Currently, it is less understood how Ci recruits cofactors to activate transcription. Here we report that hyperplastic discs (hyd), an E3 ubiquitin ligase, ca...

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Detalhes bibliográficos
Publicado no:Mech Dev
Main Authors: Wang, Guolun, Tang, Xiaofang, Chen, Yujie, Cao, Jun, Huang, Qinzhu, Ling, Xuemei, Ren, Wenyan, Liu, Songqing, Wu, Yihui, Ray, Lorraine, Lin, Xinhua
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351657/
https://ncbi.nlm.nih.gov/pubmed/24854243
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2014.05.002
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