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RNA editing of the GLI1 transcription factor modulates the output of Hedgehog signaling
The Hedgehog (HH) signaling pathway has important roles in tumorigenesis and in embryonal patterning. The Glioma-associated oncogene 1 (GLI1) is a key molecule in HH signaling, acting as a transcriptional effector and, moreover, is considered to be a potential therapeutic target for several types of...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3594290/ https://ncbi.nlm.nih.gov/pubmed/23324600 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.23343 |
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