RNA editing of the GLI1 transcription factor modulates the output of Hedgehog signaling

The Hedgehog (HH) signaling pathway has important roles in tumorigenesis and in embryonal patterning. The Glioma-associated oncogene 1 (GLI1) is a key molecule in HH signaling, acting as a transcriptional effector and, moreover, is considered to be a potential therapeutic target for several types of...

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Bibliografiska uppgifter
Huvudupphovsmän: Shimokawa, Takashi, Rahman, Mohammed Ferdous-Ur, Tostar, Ulrica, Sonkoly, Enikö, Ståhle, Mona, Pivarcsi, Andor, Palaniswamy, Ramesh, Zaphiropoulos, Peter G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Landes Bioscience 2013
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3594290/
https://ncbi.nlm.nih.gov/pubmed/23324600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.23343
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