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Reduction of Human Embryonal Rhabdomyosarcoma Tumor Growth by Inhibition of the Hedgehog Signaling Pathway

Rhabdomyosarcoma (RMS) is the most frequent soft-tissue sarcoma in children. Embryonal rhabdomyosarcoma (E-RMS) represents the most common RMS subtype, but the molecular events driving this tumor are still largely unknown. The hedgehog (HH) pathway, a major signal transduction cascade, is linked wit...

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Autors principals: Tostar, Ulrica, Toftgård, Rune, Zaphiropoulos, Peter G., Shimokawa, Takashi
Format: Artigo
Idioma:Inglês
Publicat: SAGE Publications 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3092259/
https://ncbi.nlm.nih.gov/pubmed/21779473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601910385449
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