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Hyperplastic Discs Differentially Regulates the Transcriptional Outputs of Hedgehog Signaling
Hedgehog (Hh) acts as a morphogen to activate the transcription of diverse target genes via its downstream effector Cubitus interruptus (Ci). Currently, it is less understood how Ci recruits cofactors to activate transcription. Here we report that hyperplastic discs (hyd), an E3 ubiquitin ligase, ca...
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| Veröffentlicht in: | Mech Dev |
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| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4351657/ https://ncbi.nlm.nih.gov/pubmed/24854243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mod.2014.05.002 |
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