The cell-surface proteins Dally-like and Ihog differentially regulate Hedgehog signaling strength and range during development

Hedgehog (Hh) acts as a morphogen in various developmental contexts to specify distinct cell fates in a concentration-dependent manner. Hh signaling is regulated by two conserved cell-surface proteins: Ig/fibronectin superfamily member Interference hedgehog (Ihog) and Dally-like (Dlp), a glypican th...

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Main Authors: Yan, Dong, Wu, Yihui, Yang, Yongfei, Belenkaya, Tatyana Y., Tang, Xiaofang, Lin, Xinhua
Format: Artigo
Jezik:Inglês
Izdano: Company of Biologists 2010
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2875843/
https://ncbi.nlm.nih.gov/pubmed/20501592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.045740
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