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The core protein of glypican Dally-like determines its biphasic activity in Wingless morphogen signaling
Dally-like (Dlp) is a glypican-type heparan sulphate proteoglycan (HSPG), containing a protein core and attached glycosaminoglycan (GAG) chains. In Drosophila wing discs, Dlp represses short-range Wingless (Wg) signaling, but activates long-range Wg signaling. Here, we show that Dlp core protein has...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3326419/ https://ncbi.nlm.nih.gov/pubmed/19853561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.09.001 |
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