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Structure of the protein core of the glypican Dally-like and localization of a region important for hedgehog signaling

Glypicans are heparan sulfate proteoglycans that modulate the signaling of multiple growth factors active during animal development, and loss of glypican function is associated with widespread developmental abnormalities. Glypicans consist of a conserved, approximately 45-kDa N-terminal protein core...

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Detalhes bibliográficos
Main Authors: Kim, Min-Sung, Saunders, Adam M., Hamaoka, Brent Y., Beachy, Philip A., Leahy, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156181/
https://ncbi.nlm.nih.gov/pubmed/21828006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109877108
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