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Dally-like core protein and its mammalian homologues mediate stimulatory and inhibitory effects on Hedgehog signal response

The distribution and activities of morphogenic signaling proteins such as Hedgehog (Hh) and Wingless (Wg) depend on heparan sulfate proteoglycans (HSPGs). HSPGs consist of a core protein with covalently attached heparan sulfate glycosaminoglycan (GAG) chains. We report that the unmodified core prote...

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Bibliografski detalji
Glavni autori: Williams, Elizabeth H., Pappano, William N., Saunders, Adam M., Kim, Min-Sung, Leahy, Daniel J., Beachy, Philip A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2851888/
https://ncbi.nlm.nih.gov/pubmed/20231458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001777107
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