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A Comparison of Ci/Gli Activity as Regulated by Sufu in Drosophila and Mammalian Hedgehog Response

Suppressor of fused (Su(fu)/Sufu), one of the most conserved components of the Hedgehog (Hh) signaling pathway, binds Ci/Gli transcription factors and impedes activation of target gene expression. In Drosophila, the Su(fu) mutation has a minimal phenotype, and we show here that Ci transcriptional ac...

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Pubblicato in:PLoS One
Autori principali: Oh, Sekyung, Kato, Masaki, Zhang, Chi, Guo, Yurong, Beachy, Philip A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536226/
https://ncbi.nlm.nih.gov/pubmed/26271100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135804
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