Structural basis of SUFU–GLI interaction in human Hedgehog signalling regulation

Hedgehog signalling plays a fundamental role in the control of metazoan development, cell proliferation and differentiation, as highlighted by the fact that its deregulation is associated with the development of many human tumours. SUFU is an essential intracellular negative regulator of mammalian H...

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Detalhes bibliográficos
Main Authors: Cherry, Amy L., Finta, Csaba, Karlström, Mikael, Jin, Qianren, Schwend, Thomas, Astorga-Wells, Juan, Zubarev, Roman A., Del Campo, Mark, Criswell, Angela R., de Sanctis, Daniele, Jovine, Luca, Toftgård, Rune
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2013
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852661/
https://ncbi.nlm.nih.gov/pubmed/24311597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444913028473
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