Structural basis of SUFU–GLI interaction in human Hedgehog signalling regulation

Hedgehog signalling plays a fundamental role in the control of metazoan development, cell proliferation and differentiation, as highlighted by the fact that its deregulation is associated with the development of many human tumours. SUFU is an essential intracellular negative regulator of mammalian H...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Cherry, Amy L., Finta, Csaba, Karlström, Mikael, Jin, Qianren, Schwend, Thomas, Astorga-Wells, Juan, Zubarev, Roman A., Del Campo, Mark, Criswell, Angela R., de Sanctis, Daniele, Jovine, Luca, Toftgård, Rune
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: International Union of Crystallography 2013
Gaiak:
Research Papers
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852661/
https://ncbi.nlm.nih.gov/pubmed/24311597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444913028473
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