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Structural basis of SUFU–GLI interaction in human Hedgehog signalling regulation
Hedgehog signalling plays a fundamental role in the control of metazoan development, cell proliferation and differentiation, as highlighted by the fact that its deregulation is associated with the development of many human tumours. SUFU is an essential intracellular negative regulator of mammalian H...
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| Main Authors: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3852661/ https://ncbi.nlm.nih.gov/pubmed/24311597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444913028473 |
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