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Structural basis of SUFU–GLI interaction in human Hedgehog signalling regulation
Hedgehog signalling plays a fundamental role in the control of metazoan development, cell proliferation and differentiation, as highlighted by the fact that its deregulation is associated with the development of many human tumours. SUFU is an essential intracellular negative regulator of mammalian H...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
International Union of Crystallography
2013
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3852661/ https://ncbi.nlm.nih.gov/pubmed/24311597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444913028473 |
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