Structural basis of SUFU–GLI interaction in human Hedgehog signalling regulation

Hedgehog signalling plays a fundamental role in the control of metazoan development, cell proliferation and differentiation, as highlighted by the fact that its deregulation is associated with the development of many human tumours. SUFU is an essential intracellular negative regulator of mammalian H...

詳細記述

保存先:
書誌詳細
主要な著者: Cherry, Amy L., Finta, Csaba, Karlström, Mikael, Jin, Qianren, Schwend, Thomas, Astorga-Wells, Juan, Zubarev, Roman A., Del Campo, Mark, Criswell, Angela R., de Sanctis, Daniele, Jovine, Luca, Toftgård, Rune
フォーマット: Artigo
言語:Inglês
出版事項: International Union of Crystallography 2013
主題:
Research Papers
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3852661/
https://ncbi.nlm.nih.gov/pubmed/24311597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444913028473
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