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Structure of the protein core of the glypican Dally-like and localization of a region important for hedgehog signaling
Glypicans are heparan sulfate proteoglycans that modulate the signaling of multiple growth factors active during animal development, and loss of glypican function is associated with widespread developmental abnormalities. Glypicans consist of a conserved, approximately 45-kDa N-terminal protein core...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3156181/ https://ncbi.nlm.nih.gov/pubmed/21828006 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1109877108 |
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