The core protein of glypican Dally-like determines its biphasic activity in Wingless morphogen signaling

Dally-like (Dlp) is a glypican-type heparan sulphate proteoglycan (HSPG), containing a protein core and attached glycosaminoglycan (GAG) chains. In Drosophila wing discs, Dlp represses short-range Wingless (Wg) signaling, but activates long-range Wg signaling. Here, we show that Dlp core protein has...

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Autori principali: Yan, Dong, Wu, Yihui, Feng, Ying, Lin, Sheng-Cai, Lin, Xinhua
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3326419/
https://ncbi.nlm.nih.gov/pubmed/19853561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.09.001
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