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Replicative DNA Polymerase δ but Not ε Proofreads Errors in Cis and in Trans

It is now well established that in yeast, and likely most eukaryotic organisms, initial DNA replication of the leading strand is by DNA polymerase ε and of the lagging strand by DNA polymerase δ. However, the role of Pol δ in replication of the leading strand is uncertain. In this work, we use a rep...

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Bibliografiske detaljer
Udgivet i:PLoS Genet
Main Authors: Flood, Carrie L., Rodriguez, Gina P., Bao, Gaobin, Shockley, Arthur H., Kow, Yoke Wah, Crouse, Gray F.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351087/
https://ncbi.nlm.nih.gov/pubmed/25742645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005049
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