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Replicative DNA Polymerase δ but Not ε Proofreads Errors in Cis and in Trans

It is now well established that in yeast, and likely most eukaryotic organisms, initial DNA replication of the leading strand is by DNA polymerase ε and of the lagging strand by DNA polymerase δ. However, the role of Pol δ in replication of the leading strand is uncertain. In this work, we use a rep...

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Библиографические подробности
Опубликовано в: :PLoS Genet
Главные авторы: Flood, Carrie L., Rodriguez, Gina P., Bao, Gaobin, Shockley, Arthur H., Kow, Yoke Wah, Crouse, Gray F.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351087/
https://ncbi.nlm.nih.gov/pubmed/25742645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005049
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