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Replicative DNA Polymerase δ but Not ε Proofreads Errors in Cis and in Trans

It is now well established that in yeast, and likely most eukaryotic organisms, initial DNA replication of the leading strand is by DNA polymerase ε and of the lagging strand by DNA polymerase δ. However, the role of Pol δ in replication of the leading strand is uncertain. In this work, we use a rep...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Genet
Hauptverfasser: Flood, Carrie L., Rodriguez, Gina P., Bao, Gaobin, Shockley, Arthur H., Kow, Yoke Wah, Crouse, Gray F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351087/
https://ncbi.nlm.nih.gov/pubmed/25742645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005049
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