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Replicative DNA Polymerase δ but Not ε Proofreads Errors in Cis and in Trans

It is now well established that in yeast, and likely most eukaryotic organisms, initial DNA replication of the leading strand is by DNA polymerase ε and of the lagging strand by DNA polymerase δ. However, the role of Pol δ in replication of the leading strand is uncertain. In this work, we use a rep...

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Détails bibliographiques
Publié dans:PLoS Genet
Auteurs principaux: Flood, Carrie L., Rodriguez, Gina P., Bao, Gaobin, Shockley, Arthur H., Kow, Yoke Wah, Crouse, Gray F.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4351087/
https://ncbi.nlm.nih.gov/pubmed/25742645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005049
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