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Human glial chimeric mice reveal astrocytic dependence of JC virus infection
Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease triggered by infection with the human gliotropic JC virus (JCV). Due to the human-selective nature of the virus, there are no animal models available to investigate JCV pathogenesis. To address this issue, we developed mice...
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| Udgivet i: | J Clin Invest |
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| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Clinical Investigation
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4348956/ https://ncbi.nlm.nih.gov/pubmed/25401469 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI76629 |
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