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A Competitive Advantage by Neonatally Engrafted Human Glial Progenitors Yields Mice Whose Brains Are Chimeric for Human Glia

Neonatally transplanted human glial progenitor cells (hGPCs) densely engraft and myelinate the hypomyelinated shiverer mouse. We found that, in hGPC-xenografted mice, the human donor cells continue to expand throughout the forebrain, systematically replacing the host murine glia. The differentiation...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Windrem, Martha S., Schanz, Steven J., Morrow, Carolyn, Munir, Jared, Chandler-Militello, Devin, Wang, Su, Goldman, Steven A.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2014
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4244478/
https://ncbi.nlm.nih.gov/pubmed/25429155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1510-14.2014
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