Human Glial Progenitor Cells Effectively Remyelinate the Demyelinated Adult Brain

Neonatally transplanted human glial progenitor cells (hGPCs) can myelinate the brains of myelin-deficient shiverer mice, rescuing their phenotype and survival. Yet, it has been unclear whether implanted hGPCs are similarly able to remyelinate the diffusely demyelinated adult CNS. We, therefore, ask...

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Publicat a:Cell Rep
Autors principals: Windrem, Martha S., Schanz, Steven J., Zou, Lisa, Chandler-Militello, Devin, Kuypers, Nicholas J., Nedergaard, Maiken, Lu, Yuan, Mariani, John N., Goldman, Steven A.
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8237530/
https://ncbi.nlm.nih.gov/pubmed/32433967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.107658
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