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DENND2B activates Rab13 at the leading edge of migrating cells and promotes metastatic behavior
The small guanosine triphosphatase Rab13 functions in exocytic vesicle trafficking in epithelial cells. Alterations in Rab13 activity have been observed in human cancers, yet the mechanism of Rab13 activation and its role in cancer progression remain unclear. In this paper, we identify the DENN doma...
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| Publicado no: | J Cell Biol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4347646/ https://ncbi.nlm.nih.gov/pubmed/25713415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201407068 |
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