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Regulation of DENND3, the exchange factor for the small GTPase Rab12 through an intramolecular interaction

The Rab family of small GTPases functions in multiple aspects of cellular membrane trafficking. Proteins bearing a differentially expressed in normal and neoplastic cells (DENN) domain have emerged as the largest family of Rab-activating guanine nucleotide exchange factors (GEFs). Rab12 functions in...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Xu, Jie, McPherson, Peter S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5409492/
https://ncbi.nlm.nih.gov/pubmed/28249939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.772434
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