Caricamento...
Phosphorylation of the exchange factor DENND3 by ULK in response to starvation activates Rab12 and induces autophagy
Unc-51-like kinases (ULKs) are the most upstream kinases in the initiation of autophagy, yet the molecular mechanisms underlying their function are poorly understood. We report a new role for ULK in the induction of autophagy. ULK-mediated phosphorylation of the guanine nucleotide exchange factor DE...
Salvato in:
| Pubblicato in: | EMBO Rep |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BlackWell Publishing Ltd
2015
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4467855/ https://ncbi.nlm.nih.gov/pubmed/25925668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201440006 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|