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Phosphorylation-dependent Regulation of Connecdenn/DENND1 Guanine Nucleotide Exchange Factors

Connecdenn 1/2 are DENN (differentially expressed in normal and neoplastic cells) domain-bearing proteins that function as GEFs (guanine nucleotide exchange factors) for the small GTPase Rab35. Disruption of connecdenn/Rab35 function leads to defects in the recycling of multiple cargo proteins from...

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Pubblicato in:J Biol Chem
Autori principali: Kulasekaran, Gopinath, Nossova, Nadya, Marat, Andrea L., Lund, Ingrid, Cremer, Christopher, Ioannou, Maria S., McPherson, Peter S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505046/
https://ncbi.nlm.nih.gov/pubmed/26055712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.636712
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