Intersectin‐s interaction with DENND2B facilitates recycling of epidermal growth factor receptor

Epidermal growth factor (EGF) activates the EGF receptor (EGFR) and stimulates its internalization and trafficking to lysosomes for degradation. However, a percentage of EGFR undergoes ligand‐independent endocytosis and is rapidly recycled back to the plasma membrane. Importantly, alterations in EGF...

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Bibliografiske detaljer
Udgivet i:EMBO Rep
Main Authors: Ioannou, Maria S, Kulasekaran, Gopinath, Fotouhi, Maryam, Morein, Justin J, Han, Chanshuai, Tse, Sarah, Nossova, Nadya, Han, Tony, Mannard, Erin, McPherson, Peter S
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2017
Fag:
Scientific Reports
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5709770/
https://ncbi.nlm.nih.gov/pubmed/29030480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201744034
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