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A PH-like domain of the Rab12 guanine nucleotide exchange factor DENND3 binds actin and is required for autophagy
Rab GTPases are key regulators of membrane trafficking, and many are activated by guanine nucleotide exchange factors bearing a differentially expressed in normal and neoplastic cells (DENN) domain. By activating the small GTPase Rab12, DENN domain–containing protein 3 (DENND3) functions in autophag...
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| 出版年: | J Biol Chem |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5868273/ https://ncbi.nlm.nih.gov/pubmed/29352104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001446 |
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