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A PH-like domain of the Rab12 guanine nucleotide exchange factor DENND3 binds actin and is required for autophagy

Rab GTPases are key regulators of membrane trafficking, and many are activated by guanine nucleotide exchange factors bearing a differentially expressed in normal and neoplastic cells (DENN) domain. By activating the small GTPase Rab12, DENN domain–containing protein 3 (DENND3) functions in autophag...

詳細記述

保存先:
書誌詳細
出版年:J Biol Chem
主要な著者: Xu, Jie, Kozlov, Guennadi, McPherson, Peter S., Gehring, Kalle
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5868273/
https://ncbi.nlm.nih.gov/pubmed/29352104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001446
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