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A PH-like domain of the Rab12 guanine nucleotide exchange factor DENND3 binds actin and is required for autophagy
Rab GTPases are key regulators of membrane trafficking, and many are activated by guanine nucleotide exchange factors bearing a differentially expressed in normal and neoplastic cells (DENN) domain. By activating the small GTPase Rab12, DENN domain–containing protein 3 (DENND3) functions in autophag...
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| Publicado no: | J Biol Chem |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5868273/ https://ncbi.nlm.nih.gov/pubmed/29352104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001446 |
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