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A PH-like domain of the Rab12 guanine nucleotide exchange factor DENND3 binds actin and is required for autophagy
Rab GTPases are key regulators of membrane trafficking, and many are activated by guanine nucleotide exchange factors bearing a differentially expressed in normal and neoplastic cells (DENN) domain. By activating the small GTPase Rab12, DENN domain–containing protein 3 (DENND3) functions in autophag...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5868273/ https://ncbi.nlm.nih.gov/pubmed/29352104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001446 |
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