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An Arf/Rab cascade controls the growth and invasiveness of glioblastoma
Glioblastoma is the most common and deadly malignant brain cancer. We now demonstrate that loss of function of the endosomal GTPase Rab35 in human brain tumor initiating cells (BTICs) increases glioblastoma growth and decreases animal survival following BTIC implantation in mouse brains. Mechanistic...
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| Publicado no: | J Cell Biol |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Rockefeller University Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7812876/ https://ncbi.nlm.nih.gov/pubmed/33443570 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.202004229 |
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