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Rab13 Traffics on Vesicles Independent of Prenylation

Rab GTPases are critical regulators of membrane trafficking. The canonical view is that Rabs are soluble in their inactive GDP-bound form, and only upon activation and conversion to their GTP-bound state are they anchored to membranes through membrane insertion of a C-terminal prenyl group. Here we...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Ioannou, Maria S., Girard, Martine, McPherson, Peter S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4865919/
https://ncbi.nlm.nih.gov/pubmed/26969162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.722298
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