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Rap1-GTP–interacting adaptor molecule (RIAM) is dispensable for platelet integrin activation and function in mice

Platelet aggregation at sites of vascular injury is essential for hemostasis but also thrombosis. Platelet adhesiveness is critically dependent on agonist-induced inside-out activation of heterodimeric integrin receptors by a mechanism involving the recruitment of talin-1 to the cytoplasmic integrin...

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書目詳細資料
發表在:Blood
Main Authors: Stritt, Simon, Wolf, Karen, Lorenz, Viola, Vögtle, Timo, Gupta, Shuchi, Bösl, Michael R., Nieswandt, Bernhard
格式: Artigo
語言:Inglês
出版: American Society of Hematology 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347307/
https://ncbi.nlm.nih.gov/pubmed/25336629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-08-597542
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