Rap1-GTP–interacting adaptor molecule (RIAM) is dispensable for platelet integrin activation and function in mice

Platelet aggregation at sites of vascular injury is essential for hemostasis but also thrombosis. Platelet adhesiveness is critically dependent on agonist-induced inside-out activation of heterodimeric integrin receptors by a mechanism involving the recruitment of talin-1 to the cytoplasmic integrin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Blood
Egile Nagusiak: Stritt, Simon, Wolf, Karen, Lorenz, Viola, Vögtle, Timo, Gupta, Shuchi, Bösl, Michael R., Nieswandt, Bernhard
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2015
Gaiak:
Plenary Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347307/
https://ncbi.nlm.nih.gov/pubmed/25336629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-08-597542
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak