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Rap1-GTP–interacting adaptor molecule (RIAM) is dispensable for platelet integrin activation and function in mice
Platelet aggregation at sites of vascular injury is essential for hemostasis but also thrombosis. Platelet adhesiveness is critically dependent on agonist-induced inside-out activation of heterodimeric integrin receptors by a mechanism involving the recruitment of talin-1 to the cytoplasmic integrin...
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| Publicado no: | Blood |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4347307/ https://ncbi.nlm.nih.gov/pubmed/25336629 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-08-597542 |
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