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The Rap1-RIAM pathway prefers β2 integrins
In vitro studies strongly implicate the talin-binding Ras-related protein 1 (Rap1) effector, Rap1-guanosine triphosphate–interacting adapter molecule (RIAM), in integrin activation.(1) Yet, the RIAM knockout mouse is viable and fertile and exhibits no platelet adhesion or aggregation defects,(2) cas...
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| 出版年: | Blood |
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| 第一著者: | |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4683328/ https://ncbi.nlm.nih.gov/pubmed/26679542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-09-668962 |
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