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The Rap1-RIAM-talin axis of integrin activation and blood cell function

Integrin adhesion receptors mediate the adhesion of blood cells, such as leukocytes, to other cells, such as endothelial cells. Integrins also are critical for anchorage of hematopoietic precursors to the extracellular matrix. Blood cells can dynamically regulate the affinities of integrins for thei...

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Pubblicato in:Blood
Autori principali: Lagarrigue, Frederic, Kim, Chungho, Ginsberg, Mark H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965904/
https://ncbi.nlm.nih.gov/pubmed/27207789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-12-638700
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