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The Rap1-RIAM-talin axis of integrin activation and blood cell function

Integrin adhesion receptors mediate the adhesion of blood cells, such as leukocytes, to other cells, such as endothelial cells. Integrins also are critical for anchorage of hematopoietic precursors to the extracellular matrix. Blood cells can dynamically regulate the affinities of integrins for thei...

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Bibliographic Details
Published in:Blood
Main Authors: Lagarrigue, Frederic, Kim, Chungho, Ginsberg, Mark H.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4965904/
https://ncbi.nlm.nih.gov/pubmed/27207789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-12-638700
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