Loading...

A RIAM/lamellipodin–talin–integrin complex forms the tip of sticky fingers that guide cell migration

The leading edge of migrating cells contains rapidly translocating activated integrins associated with growing actin filaments that form ‘sticky fingers' to sense extracellular matrix and guide cell migration. Here we utilized indirect bimolecular fluorescence complementation to visualize a mol...

Full description

Saved in:
Bibliographic Details
Published in:Nat Commun
Main Authors: Lagarrigue, Frederic, Vikas Anekal, Praju, Lee, Ho-Sup, Bachir, Alexia I., Ablack, Jailal N., Horwitz, Alan F., Ginsberg, Mark H.
Format: Artigo
Language:Inglês
Published: Nature Pub. Group 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589889/
https://ncbi.nlm.nih.gov/pubmed/26419705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9492
Tags: Add Tag
No Tags, Be the first to tag this record!