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A RIAM/lamellipodin–talin–integrin complex forms the tip of sticky fingers that guide cell migration

The leading edge of migrating cells contains rapidly translocating activated integrins associated with growing actin filaments that form ‘sticky fingers' to sense extracellular matrix and guide cell migration. Here we utilized indirect bimolecular fluorescence complementation to visualize a mol...

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Vydáno v:Nat Commun
Hlavní autoři: Lagarrigue, Frederic, Vikas Anekal, Praju, Lee, Ho-Sup, Bachir, Alexia I., Ablack, Jailal N., Horwitz, Alan F., Ginsberg, Mark H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Pub. Group 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4589889/
https://ncbi.nlm.nih.gov/pubmed/26419705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms9492
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