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A Simple Fragment of the Cyclic Acyldepsipeptides is Necessary and Sufficient for ClpP Activation and Antibacterial Activity

The discovery of new classes of antibacterial agents, particularly those with unique biological targets, is essential to keep pace with emerging drug resistance in pathogenic bacteria. We identified the minimal structural component of the cyclic acyldepsipeptide (ADEP) antibiotics that exhibits anti...

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Bibliografiset tiedot
Julkaisussa:Chembiochem
Päätekijät: Carney, Daniel W., Compton, Corey L., Schmitz, Karl R., Stevens, Julia P., Sauer, Robert T., Sello, Jason K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4343535/
https://ncbi.nlm.nih.gov/pubmed/25212124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201402358
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