Consequences of Depsipeptide Substitution on the ClpP Activation Activity of Antibacterial Acyldepsipeptides

[Image: see text] The acyldepsipeptide (ADEP) antibiotics operate through a clinically unexploited mechanism of action and thus have attracted attention from several antibacterial development groups. The ADEP scaffold is synthetically tractable, and deep-seated modifications have produced extremely...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:ACS Med Chem Lett
Hlavní autoři: Li, Yangxiong, Lavey, Nathan P., Coker, Jesse A., Knobbe, Jessica E., Truong, Dat C., Yu, Hongtao, Lin, Yu-Shan, Nimmo, Susan L., Duerfeldt, Adam S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2017
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682616/
https://ncbi.nlm.nih.gov/pubmed/29152050
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00320
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky