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Anti-Apoptotic NF-κB and “Gain of Function” mutp53 in Concert Act Pro-Apoptotic in Response to UVB+IL-1 via Enhanced TNF Production

In response to genotoxic stress, including UVB radiation, transcription factors NF-κB and p53 inevitably influence the cellular fate. Loss of p53 function has been attributed to malignant transformation and interferes with therapeutic interventions, whereas “gain of function” mutants even enhance tu...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:J Invest Dermatol
Päätekijät: Müller, Ines, Beissert, Stefan, Kulms, Dagmar
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340977/
https://ncbi.nlm.nih.gov/pubmed/25380350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2014.481
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