Target-Based Screen Against a Periplasmic Serine Protease That Regulates Intrabacterial pH Homeostasis in Mycobacterium tuberculosis

[Image: see text] Mycobacterium tuberculosis (Mtb) maintains its intrabacterial pH (pH(IB)) near neutrality in the acidic environment of phagosomes within activated macrophages. A previously reported genetic screen revealed that Mtb loses this ability when the mycobacterial acid resistance protease...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Zhao, Nan, Darby, Crystal M., Small, Jennifer, Bachovchin, Daniel A., Jiang, Xiuju, Burns-Huang, Kristin E., Botella, Helene, Ehrt, Sabine, Boger, Dale L., Anderson, Erin D., Cravatt, Benjamin F., Speers, Anna E., Fernandez-Vega, Virneliz, Hodder, Peter S., Eberhart, Christina, Rosen, Hugh, Spicer, Timothy P., Nathan, Carl F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340348/
https://ncbi.nlm.nih.gov/pubmed/25457457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500746z
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados