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A substrate-free activity-based protein profiling screen for the discovery of selective PREPL inhibitors

Peptidases play vital roles in physiology through the biosynthesis, degradation, and regulation of peptides. Prolyl endopeptidase-like (PREPL) is a newly described member of the prolyl peptidase family, with significant homology to mammalian prolyl endopeptidase (PEP) and the bacterial peptidase oli...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lone, Anna Mari, Bachovchin, Daniel A., Westwood, David, Speers, Anna E., Spicer, Timothy P., Fernandez-Vega, Virneliz, Chase, Peter, Hodder, Peter S., Rosen, Hugh, Cravatt, Benjamin F., Saghatelian, Alan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145007/
https://ncbi.nlm.nih.gov/pubmed/21692504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2036095
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