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A substrate-free activity-based protein profiling screen for the discovery of selective PREPL inhibitors
Peptidases play vital roles in physiology through the biosynthesis, degradation, and regulation of peptides. Prolyl endopeptidase-like (PREPL) is a newly described member of the prolyl peptidase family, with significant homology to mammalian prolyl endopeptidase (PEP) and the bacterial peptidase oli...
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| Autori principali: | , , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3145007/ https://ncbi.nlm.nih.gov/pubmed/21692504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja2036095 |
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