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Effect of Leucine Restriction on Akt/mTOR Signaling in Breast Cancer Cell Lines In Vitro and In Vivo

The mammalian target of rapamycin (mTOR) is a central controller of cell growth and is currently being investigated as a potential target in breast cancer therapy. The essential amino acid leucine has been proposed to regulate mTOR signaling. The objective of this study was to determine whether leuc...

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Bibliografiska uppgifter
I publikationen:Nutr Cancer
Huvudupphovsmän: Singh, Gopal, Akcakanat, Argun, Sharma, Chandeshwar, Luyimbazi, David, Naff, Katherine A., Meric-Bernstam, Funda
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4340095/
https://ncbi.nlm.nih.gov/pubmed/21294052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01635581.2011.523504
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