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eIF4E knockdown decreases breast cancer cell growth without activating Akt signaling
Activation of translation initiation is essential for the malignant phenotype, and is emerging as a potential therapeutic target. Translation is regulated by the expression of translation initiation factor 4E (eIF4E) as well as the interaction of eIF4E with eIF4E-binding proteins (e.g. 4E-BP1). Rapa...
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| Hlavní autoři: | , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2559956/ https://ncbi.nlm.nih.gov/pubmed/18644990 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-07-2357 |
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