Bardoxolone methyl induces apoptosis and autophagy and inhibits epithelial-to-mesenchymal transition and stemness in esophageal squamous cancer cells

Natural and synthetic triterpenoids have been shown to kill cancer cells via multiple mechanisms. The therapeutic effect and underlying mechanism of the synthetic triterpenoid bardoxolone methyl (C-28 methyl ester of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid; CDDO-Me) on esophageal cancer are unc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Drug Des Devel Ther
Egile Nagusiak: Wang, Yan-Yang, Yang, Yin-Xue, Zhao, Ren, Pan, Shu-Ting, Zhe, Hong, He, Zhi-Xu, Duan, Wei, Zhang, Xueji, Yang, Tianxin, Qiu, Jia-Xuan, Zhou, Shu-Feng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Dove Medical Press 2015
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338783/
https://ncbi.nlm.nih.gov/pubmed/25733817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S73493
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