Bardoxolone methyl induces apoptosis and autophagy and inhibits epithelial-to-mesenchymal transition and stemness in esophageal squamous cancer cells

Natural and synthetic triterpenoids have been shown to kill cancer cells via multiple mechanisms. The therapeutic effect and underlying mechanism of the synthetic triterpenoid bardoxolone methyl (C-28 methyl ester of 2-cyano-3,12-dioxoolean-1,9-dien-28-oic acid; CDDO-Me) on esophageal cancer are unc...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Drug Des Devel Ther
मुख्य लेखकों: Wang, Yan-Yang, Yang, Yin-Xue, Zhao, Ren, Pan, Shu-Ting, Zhe, Hong, He, Zhi-Xu, Duan, Wei, Zhang, Xueji, Yang, Tianxin, Qiu, Jia-Xuan, Zhou, Shu-Feng
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Dove Medical Press 2015
विषय:
Original Research
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338783/
https://ncbi.nlm.nih.gov/pubmed/25733817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S73493
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