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Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env

HIV’s envelope glycoprotein (Env) is the sole target for neutralizing antibodies. The structures of many broadly neutralizing antibodies (bNAbs) in complex with truncated Env subunits or components have been reported. However, their interaction with the intact Env trimer, and the structural determin...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Guttman, Miklos, Cupo, Albert, Julien, Jean-Philippe, Sanders, Rogier W., Wilson, Ian A., Moore, John P., Lee, Kelly K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338595/
https://ncbi.nlm.nih.gov/pubmed/25652336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7144
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