CD4-induced activation in a soluble HIV-1 Env trimer

The HIV envelope glycoprotein (Env) trimer undergoes receptor-induced conformational changes that drive fusion of the viral and cellular membranes. Env conformational changes have been observed using low-resolution electron microscopy, but only large-scale rearrangements have been visible. Here, we...

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Udgivet i:Structure
Main Authors: Guttman, Miklos, Garcia, Natalie K., Cupo, Albert, Matsui, Tsutomu, Julien, Jean-Philippe, Sanders, Rogier W., Wilson, Ian A., Moore, John P., Lee, Kelly K.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231881/
https://ncbi.nlm.nih.gov/pubmed/24931470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.05.001
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