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Antibody potency relates to the ability to recognize the closed, pre-fusion form of HIV Env

HIV’s envelope glycoprotein (Env) is the sole target for neutralizing antibodies. The structures of many broadly neutralizing antibodies (bNAbs) in complex with truncated Env subunits or components have been reported. However, their interaction with the intact Env trimer, and the structural determin...

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Foilsithe in:Nat Commun
Main Authors: Guttman, Miklos, Cupo, Albert, Julien, Jean-Philippe, Sanders, Rogier W., Wilson, Ian A., Moore, John P., Lee, Kelly K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338595/
https://ncbi.nlm.nih.gov/pubmed/25652336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7144
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