Natural Indoles, Indole-3-Carbinol (I3C) and 3,3’-Diindolylmethane (DIM), Attenuate Staphylococcal Enterotoxin B-Mediated Liver Injury by Downregulating miR-31 Expression and Promoting Caspase-2-Mediated Apoptosis

Staphylococcal enterotoxin B (SEB) is a potent superantigen capable of inducing inflammation characterized by robust immune cell activation and proinflammatory cytokine release. Exposure to SEB can result in food poisoning as well as fatal conditions such as toxic shock syndrome. In the current stud...

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Enregistré dans:
Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Busbee, Philip B., Nagarkatti, Mitzi, Nagarkatti, Prakash S.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338211/
https://ncbi.nlm.nih.gov/pubmed/25706292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118506
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