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Natural indoles, indole-3-carbinol and 3,3′-diindolymethane, inhibit T cell activation by Staphylococcal Entertoxin B through epigenetic regulation involving HDAC expression
Staphylococcal entertoxin B (SEB) is a potent exotoxin produced by the Staphylococcus aureus. This toxin is classified as a superantigen because of its ability to directly bind with MHC II class molecules followed by activation of a large proportion of T cells bearing specific Vβ-T cell receptors. C...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3874587/ https://ncbi.nlm.nih.gov/pubmed/24200994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2013.10.022 |
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