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Natural indoles, indole-3-carbinol and 3,3′-diindolymethane, inhibit T cell activation by Staphylococcal Entertoxin B through epigenetic regulation involving HDAC expression

Staphylococcal entertoxin B (SEB) is a potent exotoxin produced by the Staphylococcus aureus. This toxin is classified as a superantigen because of its ability to directly bind with MHC II class molecules followed by activation of a large proportion of T cells bearing specific Vβ-T cell receptors. C...

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Bibliografische gegevens
Hoofdauteurs: Busbee, Philip B., Nagarkatti, Mitzi, Nagarkatti, Prakash S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3874587/
https://ncbi.nlm.nih.gov/pubmed/24200994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2013.10.022
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