Indole-3-carbinol prevents colitis and associated microbial dysbiosis in an IL-22–dependent manner

Colitis, an inflammatory bowel disease, is caused by a variety of factors, but luminal microbiota are thought to play crucial roles in disease development and progression. Indole is produced by gut microbiota and is believed to protect the colon from inflammatory damage. In the current study, we inv...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Busbee, Philip B., Menzel, Lorenzo, Alrafas, Haider Rasheed, Dopkins, Nicholas, Becker, William, Miranda, Kathryn, Tang, Chaunbing, Chatterjee, Saurabh, Singh, Udai P., Nagarkatti, Mitzi, Nagarkatti, Prakash S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7030851/
https://ncbi.nlm.nih.gov/pubmed/31941837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.127551
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