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Natural Indoles, Indole-3-Carbinol (I3C) and 3,3’-Diindolylmethane (DIM), Attenuate Staphylococcal Enterotoxin B-Mediated Liver Injury by Downregulating miR-31 Expression and Promoting Caspase-2-Mediated Apoptosis

Staphylococcal enterotoxin B (SEB) is a potent superantigen capable of inducing inflammation characterized by robust immune cell activation and proinflammatory cytokine release. Exposure to SEB can result in food poisoning as well as fatal conditions such as toxic shock syndrome. In the current stud...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Busbee, Philip B., Nagarkatti, Mitzi, Nagarkatti, Prakash S.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338211/
https://ncbi.nlm.nih.gov/pubmed/25706292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118506
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