Natural Indoles, Indole-3-Carbinol (I3C) and 3,3’-Diindolylmethane (DIM), Attenuate Staphylococcal Enterotoxin B-Mediated Liver Injury by Downregulating miR-31 Expression and Promoting Caspase-2-Mediated Apoptosis

Staphylococcal enterotoxin B (SEB) is a potent superantigen capable of inducing inflammation characterized by robust immune cell activation and proinflammatory cytokine release. Exposure to SEB can result in food poisoning as well as fatal conditions such as toxic shock syndrome. In the current stud...

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Bibliographic Details
Published in:PLoS One
Main Authors: Busbee, Philip B., Nagarkatti, Mitzi, Nagarkatti, Prakash S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4338211/
https://ncbi.nlm.nih.gov/pubmed/25706292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118506
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